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Accordingly, serum sodium testing is advisable prior to beginning desmopressin therapy, especially for those over the age of 65, since these individuals are most at risk of developing hyponatremia 32.

  • A recent article provides a review of contemporary coagulation factor products and their uses in inherited disorders or coagulopathy. 28 1-Deamino-8-D-arginine vasopressin (DDAVP) or desmopressin DDAVP or desmopressin is a synthetic analog of vasopressin which lacks the vasopressor effects.
  • Nephrogenic DI may be caused by: Certain drugs, such as lithium Genetic problems High level of calcium in the body ( hypercalcemia ) Kidney disease, such as polycystic kidney disease Symptoms Central DI may be controlled with vasopressin (desmopressin, DDAVP).
  • Oxaprozin: (Major) Additive hyponatremic effects may be seen in patients treated with desmopressin and drugs associated with hyponatremia including NSAIDs.
  • Central DI is managed with hormonal replacement therapy with desmopressin (DDAVP).
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