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Aciphex 10mg 20mg – “Rabeprazole, Pariet, Rablet, Rabicip” “Duodenal Ulcers, Gastroesophageal Reflux Disease, GERD, Heartburn, Zollinger-Ellison Syndrome, Helicobacter Pylori”
Rabeprazole is a proton pump inhibitor that suppresses gastric acid production in the stomach. It has several medical uses: the management of conditions that involve excess gastric acid production (e.g. Zollinger–Ellison syndrome ), conditions that are worsened by gastric acid (e.g. ulcerations of the gastrointestinal tract), and conditions involving prolonged exposure to gastric acid (e.g. symptomatic gastroesophageal reflux disease ).
Rabeprazole’s adverse effects tend to be mild but can be serious, including deficiencies in essential nutrients, rare incidences of liver and bone damage, and dangerous rashes. Rabeprazole can theoretically contribute to numerous drug interactions, mediated both through its metabolic properties and its direct effect on acid in the stomach, though its potential for clinically meaningful drug interactions is low.
Like other medications in the proton pump inhibitor class, rabeprazole’s mechanism of action involves the permanent inhibition of proton pumps in the stomach, which are responsible for gastric acid production. Rabeprazole has a number of chemical metabolites, though it is primarily degraded by non-enzymatic metabolism and excreted in the urine. Genetic differences in a person’s drug-metabolizing enzymes may affect a person’s response to rabeprazole therapy, though this is unlikely in comparison to other proton pump inhibitors.
Rabeprazole is marketed around in the world in a variety of combinations and brand name products.
Contents
1 Medical uses
1.1 Available forms
Voriconazole inhibits CYP2C19 and may cause a decrease in the metabolism of rabeprazole if coadministered.

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